Supply High Quality Coluracetam Powder

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freemexy

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Product name: Coluracetam
Specification: 99%
CAS No.: 135463-81-9
Appearance: White powder
Molecular Formula: C19H23N3O3
Molecular Weight: 341.4042
Coluracetam is a nootropic drug of the racetam family. Coluracetam was
initially developed and tested by the Mitsubishi Tanabe Pharma
Corporation for Alzheimer’s disease. After the drug failed to reach
endpoints in its clinical trials it was in-licensed by BrainCells Inc
for investigations into major depression disorder (MDD), after being
awarded a “Qualifying Therapeutic Discovery Program Grant” by the state
of California. Findings from its Phase 2a clinical trials have suggested
that it would be an ideal medication for co-morbid MDD with generalized
anxiety disorder (GAD). BrainCells Inc is currently out-licensing the
drug for this purpose. It may also have potential use in prevention and
treatment of ischemic retinopathy and retinal and optic nerve injury.
Memory and Learning
Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same results are expected in human beings. A
study conducted by BrainCells Inc, showed a memory improvement in rats
who were given substance AF64A (a neuron-specific neurotoxin) for 8 days
along with Coluracetam in 3mg doses. These rats were put through the
standardized Morris Water Maze to mark their ability to get through it,
and even up to 72 hours after the last 8mg dose, they were still able
to. Another key finding of this study was that the results were still
apparent 3 days after the last dose, even though the serum concentration
of Coluracetam was negligible.
Depression and Anxiety
BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with
GAD (generalized anxiety disorder). However, the differences were most
pronounced in those who didn’t find relief in using standard
antidepressants. After one dose, there were no noticeable differences,
but after 2 doses at 80mg, 36% had improved scores during a depression
assessment test.
Eyesight
Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn’t any
conclusive evidence to support the mechanisms behind this benefit,
experts believe that Coluracetam works in the part of the brain that
runs visual processes.
Dosage
Since the study subjects were rats, there aren’t any recommended human dosages, but there is a general guideline for conversion.In rats,
the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using
allometric scaling, the dose becomes 2.9 mg/kg in humans, so the average
dose should not exceed 203.5 mg daily for someone in a typical weight
class.
There isn’t very much information to indicate toxicity of Coluracetam, although doses given at the above increments showed no
negative side effects. If you haven’t used a nootropic before, you may
develop headache after use, which is a common in first time users. By
stacking the Coluracetam with Choline, you’ll reduce this risk.
Posted 12 Oct 2019

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Posted 18 Mar 2020

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